The song is indeed 'Homeward Bound' originaly performed by Simon & Garfunkle but the one in the MasterCard commercial is a cover by some unknown commercial jingle artist. Too bad, that rock riff style cover sounds great too!
~TRD

> I was trying to find the same song on the Mastercard commercial and got a response. Someone suggested that it might be Simon and Garfunkel's 'Homeward Bound'